AGED Diagnostics
We are a team of geneticists and hepatologists who started our pursuits in 2018 when we realized the tools we were using in research were not being well translated into the clinic. We saw an opportunity to apply genomic innovation to improve the lives of patients. Our team is developing the most accurate blood test for liver disease (also known as nonalcoholic steatohepatitis or NASH).
Unmet Medical Needs
While 1 in 3 Americans or 100 million people have liver disease, many are unaware until the disease has progressed to later stages at which point patient outcomes are poor and healthcare spending can cost up to $1,000,000 per patient. Conversely, early detection of liver disease is not only treatable, but fully reversible.
The bronze standard diagnostic tool is a liver biopsy, which is expensive, invasive, prone to sampling error and bleeding. Imaging tools fail in nearly 60% of patients and there are zero accurate noninvasive tools.
60%
Our Business
AGED Diagnostics is using genomic innovation to develop the most accurate blood test for liver disease to help physicians keep patients in the monitoring program, reduce the financial burden for health insurers and improve patient outcomes through early detection and intervention.
What We Do
AGED tools can differentiate benign from advanced liver disease and simultaneously stage fibrosis (liver scarring). Our technology uses a targeted genomic sequencing assessment to measure the concentration of target biomarkers (genetic signatures) in circulation. The presence of biomarkers past a defined concentration indicates a diagnosis of liver disease (NASH) and/or fibrosis.
CORE TECHNOLOGY
Differentiate Simple Steatosis from NASH
Identify Advanced Fibrosis
Exclude Other Chronic Liver Diseases
Our Partners
Meet The Team
PhD in Human Genetics
Expert in genomics research and molecular diagnostics development
Eric Eastman
Acting Chief Operations Officer
Rachel Zayas
Founder & CEO
Geneticist, MBA
Healthworx (CareFirst) Fellow, Halcyon Fellow
Expert in biomarker development
Naim Alkhouri, MD
Clinical Collaborator
Chief Medical Officer,
Director of the Fatty Liver Program Arizona Liver Health
Coleman Irving Smith, MD
Clinical Collaborator
Transplant Hepatologist
MedStar Georgetown University Hospital
Jasmine Kirksey
Director of Laboratory Operations
Dr. Bongsoo Park
Lead Bioinformaticist
Bioinformatics CRO
Researcher at NIH, Lecturer John Hopkins